"He had good velocity and good movement to his two-seamer," said Padres manager Bud Black of Cashner, who got nine ground-ball outs with the pitch. "He did a good job keeping the ball down with his two-seamer."
San Diego scored three runs off Rockies left-hander Franklin Morales in the second, as Alex Castellanos began the rally with a single in his first Padres at-bat since being claimed off waivers Thursday from the Rangers.
Jackson followed with a two-run homer to left, while catcher Rene Rivera doubled, advanced to third on Cashner's single and scored on a wild pitch.
"I threw a lot of strikes, made my pitches," Morales said. "Sometimes you miss your pitch, and that's when you get hit."
Padres catcher Yasmani Grandal was 1-for-2 in his Cactus League debut coming off last season's ACL injury, while first baseman/outfielder Tommy Medica continued his torrid spring by going 1-for-3.
The Rockies got two hits a piece from left fielder Carlos Gonzalez and third baseman Nolan Arenado, while first baseman Justin Morneau was 0-for-2 in his first action of the spring.
Up Next: Left-hander Jorge De La Rosa looks to continue his steady improvement Tuesday in his third Cactus League start at 2:05 p.m. MT in Mesa, Ariz., against the Cubs. De La Rosa, Colorado's likely Opening Day starter, allowed one run on three hits and walked one on Friday against the Angels.
Cash Kruth is a reporter for MLB.com. Follow him on Twitter at @cashkruth. This story was not subject to the approval of Major League Baseball or its clubs.