DJ LeMahieu singled off Brewers reliever Rob Wooten to open the inning. Pinch-hitter Charlie Culberson followed with a line drive to right field, only to see the Brewers' Ryan Braun rush inward to make the catch. Braun noticed how far LeMahieu was off first base and doubled him off.
First-base umpire Mike DiMuro called LeMahieu out, and the ruling stood after replay.
The Brewers then went to Tom Gorzelanny, who forced a Charlie Blackmon groundout to end the game.
Weiss is 8-for-16 on replay challenges this season.
Thomas Harding is a reporter for MLB.com. Follow him on Twitter @harding_at_mlb. This story was not subject to the approval of Major League Baseball or its clubs.