To replace the pair, they recalled lefty Christian Friedrich and catcher Jackson Williams, who each were available for the team's Wednesday night game against the Giants.
Williams, who came up through the Giants organization, is hitting .256 with four home runs and 34 RBIs in 72 games with Triple-A Colorado Springs this season. The 28-year-old spent three days on the Major League roster in late June but did not appear in a game.
Friedrich returns to the Rockies a rejuvenated pitcher after a two-month banishment to the Minors.
He went 0-3 with a 9.45 ERA as he was rocked to the tune of 14 earned runs on 21 hits and eight walks during 13 1/3 innings in late June/early July.
After arriving at Triple-A, the former first-round pick was notified he'd spend the rest of the season in the bullpen. A lifelong starter, Friedrich wasn't initially very keen on the idea, but he quickly grew receptive to it and said Wednesday that the change has rejuvenated him.
"It's brought the aggressiveness back out, the competitive edge," Friedrich said. "Thinking about it one pitch at a time brings out a side of you that you might have lost sight of when you're thinking of the whole game as a big picture as a starter. It's been a smooth transition.
"You're trying to get an out with each pitch. That's not to say you weren't as a starter, but you set up guys as you go through the order for three different times. Right now, it's 'here it is, here's my stuff, let's see what you can do with it'."
Ryan Hood is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.